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CJC-1295 is a synthetic analogue of the first 29 amino acids of endogenous GHRH the biologically active portion

Metformin: Metformin works by reducing the amount of glucose produced by the liver and improving insulin sensitivity, leading to a decrease in appetite and potential weight loss

While publication bias cannot be entirely excluded, a comprehensive search strategy across multiple databases was used to minimise this risk

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It is important to note that GLP-1 receptor agonists are not currently licensed for the treatment of rheumatoid arthritis or other inflammatory conditions in the UK

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